5th Mentored Paper Initiative (Winter 2022)

Topics

MPI5.1: Does a low carbohydrate diet have a significant role to play in the prevention and/or treatment of neuro-cognitive diseases (i.e., Alzheimer’s disease)?

 

MPI5.2: What are the most important factors at play in men’s health (reproductive, cardiovascular, oncological) that contribute to gender disparity in life expectancy?

 

MPI5.3: Is a sex-specific approach to the management of type-2 diabetes warranted?

 

MPI5.4: What therapeutic options are available to patients with multiple sclerosis?

 

MPI5.5: How is multiple sclerosis different from other neurodegenerative diseases?

 

MPI5.6: What is the role of ageing in multiple sclerosis pathology?

 

MPI5.7: What is the role of footcare for individuals who are homeless?

 

MPI5.8: How effective are injectable neuroleptics for individuals with schizophrenia?

 

MPI5.9: In surgical training programs, how does the use of surgical simulation compare to other surgical training as measured by medical professionals’ (staff, residents, medical students) skills and confidence?

 

MPI5.10: What are some of the potential mechanisms for exercise to promote sleep?

 

MPI5.11: Why does exercise protect cognitive functions in ageing?

 

MPI5.12: Can the implementation of a machine learning model within a non-knowledge-based clinical decision support system be useful for front-line workers in psychiatry?

 

MPI5.13: How can innovative technologies in artificial intelligence (AI) create a gold standard for disease modelling within psychiatry?

 

MPI5.14: Why is bioluminescence imaging (BLI) & magnetic resonance imaging (MRI) employed simultaneously for tracking tumour growth in bioluminescent organisms?

 

MPI5.15: Explain how the Silica Nanoparticles are used for drug delivery while controlling the chemical properties of stimulation of the targeted area.

 

MPI5.16: Why is the computational analysis of the musculoskeletal system important for complementing exoskeleton design research?

 

MPI5.17: How can short-term music training help be hearing and speech perception in children with cochlear implants?

 

MPI5.18: What is the relationship between age-related hearing loss and dementia/dementia risk?

 

MPI5.19: What are the cognitive deficits (i.e., memory, executive function, language) associated with those with amnestic mild cognitive impairment, a prodromal stage of Alzheimer's disease and other dementias?

 

MPI5.20: Memory storage is a topic that has dumbfounded the neuroscience community for decades and has yet to be. Over the years many theories have been explored to determine where memories are stored and how they are recalled. To what extent are varying brain regions, neurophysiological functions and/or components involved in the process of storing a memory?

 

MPI5.21: To what extent does neuroepigenetics play a role in either neurophysiological or psychological conditions (this can include studying a mental disorder, neurological disease, etc)? How has it affected its diagnosis, understanding of the condition and treatment options?

 

MPI5.22: CRISPR, a novel approach to genome editing, has been used for a variety of applications, including as a potential cancer therapy. What literature exists surrounding these efforts?

 

MPI5.23: What is the evidence for sex-specific molecular studies? (i.e. the pros and cons of using male vs female cells in a scientific study)

 

MPI5.24: What efforts are currently underway or have been made in using CRISPR for the treatment of human genetic diseases in humans or in model organisms (eg. primates)? What are the potential pros and cons of human genome editing?

 

MPI5.25: What advantages and disadvantages are there when engineering a cell with a minimal genome?

 

MPI5.26: How has bioinformatics advanced essential gene predictions and what are the pitfalls?

 

MPI5.27: How is the production of polyhydroxyalkanoates (PHAs) improved and optimized?

(i.e. metabolic and genome engineering, process optimization, etc.)

 

MPI5.28: What therapeutic opportunities can you see in the tumour microenvironment?

 

MPI5.29: What is the potential for tumour subtyping to influence clinical practice?

 

MPI5.30: What are the origins of cancer-associated fibroblasts?

 

MPI5.31: How do blood flow patterns prevent and/or promote plaque build-up in vessels, leading to cardiovascular disease?

 

MPI5.32: What therapies and therapeutic targets are used to combat a leading cause of death globally, cardiovascular disease?

 

MPI5.33: As a society, how can we decrease the risk of developing cardiovascular disease?

 

MPI5.34: How do host microRNAs impact the gut epithelial barrier during inflammatory bowel disease?

 

MPI5.35: How do host microRNAs impact the gut microbiota during inflammatory bowel disease?

 

MPI5.36: What are the advantages and disadvantages of using microRNAs as either diagnostic or therapeutic tools for gut health and disease?

 

MPI5.37: What are the major stresses that drive the formation, progression, and metastasis of cancer?

 

MPI5.38: Are there "turning points” (hallmarks) during cancer progression which can be identified for therapeutic manipulation?

 

MPI5.39: How do tumour cells transmit their epigenetic features to daughter cells and maintain the malignant phenotype?

 

MPI5.40: What does the trajectory of treatment in patients suffering from Acute Myeloid Leukemia look like?

 

MPI5.41: How can identifying measurable residual disease in Acute Myeloid Leukemia (AML) and Acute Lymphoid Leukemia (ALL) patients aid in prognosis?

 

MPI5.42: What are the methods available for identifying measurable residual disease in leukemia patients, and how are they able to detect these cells?

 

MPI5.43: How will developments in artificial intelligence shape the future of organic chemistry?

 

MPI5.44: How can nanotechnology help in reaching United Nations (UN) sustainability goals?

 

MPI5.45: What are the benefits of using nanomaterials in an industrial sector of your choice (examples include aeronautics, medical devices, electronics, etc.) and why?